Biotechnology and Genetic Engineering
Biotechnology Vol. 5: Gene and Protein Engineering
Description
"The scientists’ ability to design and synthesize new genes and so the novel proteins is the most exciting progress made in the field of molecular biology about 35 years back. The gene and protein engineering has virtually transformed the stream of life sciences. It is now possible to change a protein by replacing and removing the existing or adding new amino acid residues. Even, two or more proteins can be fused together to form a new hybrid protein. In recent times, due to enormous development in genetic engineering and high-throughput technologies, protein engineering and its applications have become significantly important and popular. This field has grown and continues to grow rapidly. This volume represents an excellent collection of articles to help the readers catch up with the latest advancements made in the field of gene and protein engineering. Although, the temptation in compiling and finalizing this volume was to concentrate on applications, the basic technical introduction to the subject is also provided. The topics covered in this volume include: • Current advancements in next generation sequencing • Engineered small RNA for gene regulation and therapy• Micro RNAs as potential biomarkers for toxicity diagnosis in body • Apoptosis and genes involved in it• Gene expression profiling for cancer diagnosis• Characterization of craniosynostosis in Asian Indian children • Craniosynostosis and genetic engineering• Recent trends in genetic engineering based fungal disease resistance in crops• Gene therapy for correcting birth defects and neurological disorders• Loop-mediated isothermal amplification and its alternatives in plant diagnosis approaches • Genetic engineering of citrus for useful agronomic traits• Production and industrial applications of genetically engineered xylanases • Proteomics study using liquid chromatography-mass spectrometry • Protein engineering strategies for enzyme design• Production of recombinant therapeutic proteins in yeast• Rational design of fully mouse to fully monoclonal antibodies for immunotherapy • Peroxynitrite modified antigen as biomarker in systemic lupus erythematosus• Review on nutrigenetics and nutrigenomics • Genomic technologies for reducing the antinutrients in legumes • Structural and molecular features of L-Tyrosinase enzyme The volume 5 contains 20 chapters from 53 researchers and/or academicians representing 9 nations, namely China, India, Iran, Mexico, Oman, Switzerland, Taiwan, U.K. and United States of America giving an overview of the various research activities being carried out in different parts of the world in the field of Gene and Protein Engineering."
Table of Contents
Foreword to the Series; About the Editors; List of Contributors; About the Series; Preface; Applications of Next Generation Sequencing (INDIA); Small Regulatory RNA: A New Era of Gene Regulation and Therapy (INDIA); Circulating MicroRNAs in Body Fluid: A New Potential Biomarker for Toxicity Diagnosis (INDIA); Apoptosis and Involved in it Genes (INDIA); Trends in Gene Expression Profiling: An Overview of Challenges for Cancer Diagnosis (INDIA); Genotypic and Phenotypic Characterization of Cranio-synostosis in Asian Indian Children for Future Strategy Involving Molecular Medicine (INDIA); Craniosynostosis and Genetic Engineering (INDIA); Recent Trends in Genetic Engineering Based Fungal Disease Resistance in Crops (INDIA); Gene Therapy in Correcting Birth Defects and Neurological Disorders (INDIA); Application of Loop-Mediated Isothermal Amplification (LAMP) and Its Alternatives in Plant Diagnosis Approaches (IRAN, U.K); Genetic Engineering of Citrus for Useful Agronomic Traits (INDIA); Recent Progress in Genetically Engineered Xylanases: Production and Industrial Applications (INDIA); Proteomics Study Using Liquid Chromatography-Mass Spectrometry (TAIWAN); Protein Engineering Strategies for Enzyme Design (CHINA); Production of Recombinant Therapeutic Proteins in Yeast (USA); Rational Design of Fully Mouse to Fully Human Monoclonal Antibodies for Immunotherapy (IRAN, USA, SWITZERLAND); Peroxynitrite Modified Antigen: An Immunological Biomarker in Systemic Lupus Erythematosus (INDIA, OMAN); Nutrigenetics and Nutrigenomics: A General Review (MEXICO); Effort Towards Reducing the Antinutrients in Legumes Through the Application of Genomic Technologies (INDIA); L-Tyrosinase - A Multifunctional Enzyme: Structural and Molecular Features (INDIA); Appendix-I: Table of Contents of Biotechnology Series Vols. (1 to 12); Subject Index