Biotechnologie et Génétique Ingénierie
Biotechnologie Vol. 7: Drug Discovery
Description
Drug discovery et development is a long term process avec involvement de multidisciplinary approach starting from lead identification to pathway analysis to late stage clinical development. Un parallel processing de biological, chemical, pharmaceutical et clinical data can provide a solution to le drug discovery puzzle. This volume mainly concentrates sur three main sections viz. discovery de lead molecules, updates sur antimicrobials et current status de biotherapeutics development, et is hoped to be an essential reading pour pharmacologists, medicinal chemists et pharmaceutical scientists working en academia et industry. Le following topics have been covered en this volume: • Discovery de novel lead molecules from plant sources • Nouveau formulations et applications de natural genistein • Bacterial cell wall as reservoir de novel drug targets • General mechanism de bacterial virulence, role de quorum sensing en determining virulence et biofilm traits en bacteria • Antimicrobial characteristics de Burkholderia produced metabolites • Microbes based therapy pour le treatment de cancer • Développement et production de natural et synthetic antimicrobial peptides • Regulatory processes pour controlling le biosynthesis de Beta-lactam antibiotics en Penicillium chrysogenum et Acremonium chrysogenum fungi • Review de stem cell research en human et veterinary therapeutics • Review sur depression et its treatment by new antidepressant molecules • Diuretic effects de urea transporter inhibitors • BCL2 inhibitors pour target specific cancer therapy • Trends en development de non-steroidal anti-inflammatory drugs • Review sur biological effects de Ecdysteroids et Bisacylhydrazene • Développement de novel polyene antifungal formulations • Application de biotechnology en molecular pharmacognosy • Evaluation de toxic risk en drug therapy • Status de biotherapeutics development en Inde • Best practices followed en biopharmaceutical drug development Le volume 7 contains 19 chapters from 51 researchers and/or academicians representing 6 nations, namely China, Egypt, Inde, Israel, Romania et Spain giving an overview de le various research activities being carried out en different parts de le world en le field de Drug Discovery.
Table des matières
Foreword to le Series; À propos de le Editors; List de Contributors; À propos de le Series; Preface; Discovery de Novel Lead Molecules from Plante Sources; Natural Compound Genistein: From Consecrated to Nouveau Utilizations et Formulations; Bacterial Cell Wall: Un Reservoir de Novel Drug Targets; Bacterial Virulence, Biofilm et Quorum Sensing as Promising Targets pour Antipathogenic Drug Discovery et le Role de Natural Products; Burkholderia - Un Repertoire de Antimicrobial Agents; Microbes as Antitumour Agents: Un Emerging Approche pour Cancer Therapy; Novel et Synthetic Antimicrobial Peptides: Développement et Strategies; Regulatory Processes Contrôleling le Biosynthesis de Beta-lactam Antibiotics en Penicillium chrysogenum et Acremonium chrysogenum; Stem Cell et Drug Discovery: Novel Approche en Human et Vétérinaire Therapeutics; Discovery de Nouveau Antidepressants by Using Animal Models Along avec Various Aspects de Depression; Discovery de Urea Transporter Inhibitors as Novel Diuretics; Targeted Cancer Therapy: Le Role de BCL2 Inhibitors; Anti-inflammatory Drugs: Trends en Développement de Non-steroidal Anti-inflammatory Drugs NSAIDs; Biologique Effects de Ecdysteroids et Their Non-Steroidal Agonist Bisacylhydrazines – Un Review; Polyene-Intralipid Formulation Antifungals Against Invasive Mycoses; Le Application de Biotechnologie en Moléculaire Pharmacognosy; Evaluation de Toxic Risk en Drug Therapy; Status de Biotherapeutics Développement en Inde; Biopharmaceutical Drug Développement Process as le Key en Drug Discovery; Appendix-I: Table de Contents de Biotechnologie Series Vols. (1 to 12); Subject Index