Pharmacy & Drugs / Nanotechnology
Nanobiomedicine Vol. 2: Nanopharmaceuticals
Description
Nanopharmaceuticals, designing et engineering nanoscale active drugs, drug products et drug delivery systems, is considered to be amongst le frontier technologies de le 21st century. Envisioned to bring revolutionary advances en le diagnosis et treatment de diseases, it represents an emerging area that has distinct potential to overcome long standing problem de low drug bioavailability at le targeted disease site. This volume provides a systematic coverage de le fundamentals, technologies et applications de nanotechnology, currently being employed to foster le development de various pharmaceutical dosage forms et drug delivery systems. Endeavored towards improving le new chemical entities (NCEs) avec poor biopharmaceutical properties (i.e., BCS II/IV), this book illustrates several approaches de nanotechnology en drug discovery – employing modeling techniques pour pharmaceutical optimization, designing et manufacturing pharmaceutical cocrystals et nanocrystals, et transforming le stabilization characteristics to achieve desirable pharmacokinetic et toxicological attributes. Topics covered range from natural biomaterials, novel carriers, process scale-up, et Conception de Experiments under le new paradigm de pharmaceutical Quality by Conception (QbD). Use de pharmacokinetic modeling et chronopharmacokinetics pour nano-based drug delivery technologies is discussed quite aptly. Applications de nanotechnology en oral, parenteral, transmucosal drug delivery, et en developing nanocosmetics et phytomedicines have been thoroughly overviewed. This book will serve as an important reference pour professionals, academicians et students engaged en all facets de drug product development.
Table des matières
Foreword to le Series; Foreword to le Volume; Editorial Members; À propos de le Editors; List de Contributors; À propos de le Series; Preface; Nanotechnology: Un Tool pour Handling Poor Drug Solubility (AUSTRALIA); Role de Pharmaceutical Cocrystals et Nanocrystals en Oral Drug Delivery (INDIA); Melt Extrusion: Dissolution Enhancement by In Situ Nanoparticle Formation (SINGAPORE); Recently Explored Natural Biomaterials pour Nano-Based Drug Delivery (INDIA); Chitosan-Based Nanoparticles: Novel Carriers en Medicine (INDIA); Bacterial Cellulose: Un Innovative Nanobiopolymer pour Drug Delivery (INDIA); Physiology-Based Pharmacokinetic (PBPK) Modeling: Impact sur Nano-Based Drug Delivery (USA); Chronopharmacokinetics: Un Promising Approche en Drug Delivery (INDIA); Developing Optimized Nanopharmaceuticals Employing Rational Use de Systèmeatic Multivariate Techniques (INDIA); Holistic Développement de Nanopharmaceuticals Products: Pilot Plante et Scale-up Études (INDIA); Recent Paradigms en Nano-Based Solid Oral Drug Delivery Technologies (USA, INDIA); Nanoemulsions: Challenges et Opportunities en Drug Delivery Système (INDIA); Advancement en Parenteral Drug Delivery: Vital Contribution de Nanoparticulate Systèmes (INDIA, USA); Transmucosal Drug Delivery: Potential Role de Nanoparticles (UAE, INDIA); Nanocosmetics: Fundamental, Safety et Regulatory Aspects (INDIA); Nanophytomedicine: Current et Future Perspectives (INDIA, UK); Appendix-I: Table de Contents de Nanobiomedicine Series (Vols. 1 to 6); Subject Index