Pharmacy & Drugs / Nanotechnology
Nanobiomedicine Vol. 3: Nanotheranostics
Description
Theranostics, a harmonious merger of therapeutics and diagnostics, paves the path to personalized medicine. Theranostics plays a crucial role in steering every step of drug development process, primarily the biomarker discovery, target selection and validation of biomarkers, dose optimization and monitoring of the drug response. This book - a compilation of current status of the burgeoning progress in the field of nanotheranostics - presents multidisciplinary chapters focusing on advanced techniques for imaging, including the in vivo multimodal imaging of tumors, drug delivery, diagnosis and site-specific targeting. The book delineates the applications of different types of nanostructures, viz. liposomes, polymer-based nanoparticles, solid lipid nanoparticles, ceramic-based nanoparticles, albumin nanoparticles, superparamagnetic iron oxide nanoparticles, semiconductor nanoparticles, dendrimers, silica-based nanocomposites and carbon nanotubes in drug delivery and as novel theranostic systems. It also focuses on metallic nanoparticles such as gold nanorods-based contrast agents for optoacoustic tomography, photothermal therapy and preclinical investigations. Further, the advent of metallo-fullerenes and nano-shells, the most recently developed metallic nanoparticles, as newer strategies employed in the treatment of various cancers and as theranostics agents, is aptly described. Use of novel neurological models, proteomic-based biomarker identification for cancer diagnostics and the futuristic applications of nanoparticles as platforms for theranostics, consisting of nucelic acid-based therapies in dermatology, radiolabeling nanoparticles for in vivo molecular imaging and nuclear scintigraphy, are presented in this volume too. This book is an elaborated treatise for researchers, young and experienced both, to relish and savor the current status of theranostics and its various applications available today and imminent in the near future.
Table of Contents
Foreword to the Series; Foreword to the Volume; Editorial Members; About the Editors; List of Contributors; About the Series; Preface; Semiconductor Nanoparticles: Emerging Role in Theranostics (India); Superparamagnetic Iron Oxide Nanoparticles (SPIONS): Formulation Development Strategies and Applications (INDIA); Role of Metallic Nanoparticles in Targeted Drug Delivery Systems (INDIA); Nucleic Acid-Based Therapy in Dermatology (USA); Imaging in Targeted Drug Delivery for Theranostic Applications (USA); Nuclear Scintigraphy: A Promising Tool to Evaluate Novel and Nano-Based Drug Delivery Systems (INDIA); Biocompatible Gold Nanorods for Biomedical Applications and Preclinical Investigations (USA); Nanobiotechnology: Expediency in Human Health and Medicine (INDIA, KOREA); Radiolabeling of Nanoparticles for In Vivo Imaging and Biodistribution Analysis (INDIA); Proteomics-Based Biomarker Identification in Oral Squamous Cell Carcinoma (AUSTRALIA, INDIA); Neurological Models for Evaluation of Drug Delivery Systems (USA); Recent Advances in the Applications of Metallic Nanoparticles, and their Platforms as Theranostic Agents (SAUDI ARABIA); Emerging Newer Nanotechnology-Enabled Techniques for Imaging Cancer (USA); Silica-Based Nanoparticles for Theranostic Applications (INDIA); Novel Nanomedicinal Formulations for Targeted Chemotherapy and Diagnostics (USA, INDIA); Appendix-I: Table of Contents of Nanobiomedicine Series (Vols. 1 to 6); Subject Index