Pharmacology
Principes de Expérimental Pharmacology
Description
Approche to le experimental pharmacology has been changed en past few years. It is due to le advancement en learning through computer based experimentations. Although it is effective, less expensive et save lives de thousand de experimental animals, understanding et implementation de such kind de knowledge pour further study or en industries had certain limitations. Hence, there is a modify en le usual approach de gaining de knowledge, practical skills et developing attitudes en students. Un need has, therefore, been felt pour a manual that documents why et how a practical should be conducted. This book has fulfilled le need and, en fact, gone beyond merely fulfilling le need. Le book has been written keeping en mind le preferred standard shift en le practical curriculum pour undergraduate medical students. Le chapters en le book have been prepared en sections like in-vivo pharmacology et Ex-vivo pharmacology mainly pour clarity et convenience. Le book covers all le possible exercises en pharmacology that can be carried out by most institutions, avec minimal resources. Un useful feature de this book is le sufficient use de diagram, which will help not only le trainee teachers but also le students to understand le mechanism. Each chapter is neatly presented avec concision et precision. Le objectives de learning are clearly defined, although they could well have been stated at le beginning de le chapter. Le clear et relevant illustrations can substitute le lack de materials, which may be le case at some centers. Le section sur experimental pharmacology describes those experiments that are necessary pour le student to understand le fundamental mechanisms de drug action. Le author also emphasizes ethics en animal experimentation.
Table des matières
À propos de le Authors, Preface, To study introduction de experimental pharmacology, To study introduction et basic principles de commonly used laboratory wares pour isolated preparations en experimental pharmacology, To study commonly used laboratory animals en experimental pharmacology, To study common routes de drug administration en laboratory animals, To study preparation et purpose de physiological salt solution/drug solution, To study various anesthetic used pour laboratory animals, To study different techniques de euthanasia en laboratory animals, To study methods pour collection de blood, body fluid et urine en various experimental animals, Introduction à CPCSEUn et IAEC guidelines, Screening de drugs sur isolated preparations (ex-vivo), Bioassay, To study effect de drugs sur ciliary muscle movement en frog, Screening de analgesic drugs (in-vivo), Screening de anti-inflammatory drugs (in-vivo), Screening de drugs acting sur CNS (in-vivo), Local anesthetic activity, To study mydriatic et miotic effect de topically applied drugs sur rabbit’s eye, To study vasodilator/vasoconstrictor effect de drugs sur blood vessels by using perfused rabbit ear (Pissemski method). Diuretic activity, To study effect de hepatic microsomal enzyme inducer inhibitor sur le duration de action de Phenobarbital induced sleeping time, To study antipyretic activity by using telethermo- meter method en rats/rabbit, To study anti-secretory et ulcer protective activity en rats by using pylorus ligation technique (SHAY rat model), To study introduction de ED50 et LD50 value, To study introduction de computer assisted learning en pharmacology, References, Subject Index